KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP2A1
All Species:
37.88
Human Site:
S581
Identified Species:
75.76
UniProt:
O14983
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14983
NP_004311.1
1001
110252
S581
E
E
M
V
L
D
D
S
A
R
F
L
E
Y
E
Chimpanzee
Pan troglodytes
XP_001142958
1000
109764
S580
E
E
M
V
L
D
D
S
A
R
F
L
E
Y
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849777
993
109198
S580
E
E
M
I
L
D
D
S
A
R
F
M
E
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R429
994
109407
S581
E
E
M
V
L
D
D
S
A
K
F
M
E
Y
E
Rat
Rattus norvegicus
Q64578
994
109391
S581
E
E
M
V
L
D
D
S
A
K
F
M
E
Y
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505463
1167
128710
S750
E
E
M
N
L
D
D
S
A
N
F
I
K
Y
E
Chicken
Gallus gallus
P13585
994
109005
S581
E
D
M
M
L
V
D
S
T
K
F
A
E
Y
E
Frog
Xenopus laevis
NP_001080404
996
109455
S581
E
D
M
V
L
E
D
S
T
K
F
V
D
Y
E
Zebra Danio
Brachydanio rerio
NP_001007030
994
108738
S581
E
E
M
N
L
E
D
S
T
K
F
A
E
Y
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22700
1020
111683
S581
D
E
M
D
L
G
D
S
T
K
F
Y
Q
Y
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SY55
998
109042
Q570
K
T
V
P
H
G
Q
Q
T
I
S
Y
D
N
E
Baker's Yeast
Sacchar. cerevisiae
P13586
950
104552
T560
L
T
L
S
D
S
S
T
P
L
T
E
D
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
N.A.
95.5
N.A.
95.9
96
N.A.
71.1
90.2
89.1
85.2
N.A.
69.8
N.A.
N.A.
N.A.
Protein Similarity:
100
97.1
N.A.
98
N.A.
97.9
98
N.A.
79
95
95.5
92.2
N.A.
81.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
86.6
86.6
N.A.
73.3
60
60
66.6
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
86.6
80
93.3
80
N.A.
73.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.5
31.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
71.2
52.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
50
0
0
17
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
17
0
9
9
50
84
0
0
0
0
0
25
0
0
% D
% Glu:
75
67
0
0
0
17
0
0
0
0
0
9
59
0
92
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
84
0
0
0
0
% F
% Gly:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
9
0
9
0
0
9
% I
% Lys:
9
0
0
0
0
0
0
0
0
50
0
0
9
0
0
% K
% Leu:
9
0
9
0
84
0
0
0
0
9
0
17
0
9
0
% L
% Met:
0
0
84
9
0
0
0
0
0
0
0
25
0
0
0
% M
% Asn:
0
0
0
17
0
0
0
0
0
9
0
0
0
9
0
% N
% Pro:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
9
0
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% R
% Ser:
0
0
0
9
0
9
9
84
0
0
9
0
0
0
0
% S
% Thr:
0
17
0
0
0
0
0
9
42
0
9
0
0
0
0
% T
% Val:
0
0
9
42
0
9
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
17
0
84
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _